Aminoethyl-SS-ethylalcohol

SKU T14257-100 mg Category Brand:

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Products Details

Product Description

– Aminoethyl-SS-ethylalcohol (Compound 3) is an Alkyl-Chain-based PROTAC linker can be used in the synthesis of PROTACs[1]. Aminoethyl-SS-ethylalcohol is also a glutathione cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[2].

Web ID

– T14257

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C4H11NOS2

References

– Zhang H, et al. Striking a Balance between Carbonate/Carbamate Linkage Bond- and Reduction-Sensitive Disulfide Bond-Bearing Linker for Tailored Controlled Release: In Situ Covalent-Albumin-Binding Gemcitabine Prodrugs Promote Bioavailability and Tumor Accumulation. J Med Chem. 2018 Jun 14;61(11):4904-4917.

CAS Number

– 15579-01-8

Molecular Weight

– C4H11NOS2

SMILES

– OCCSSCCN

Target

– Others

Pathway

– Antibody-drug Conjugate/ADC Related

Product type

– PROTAC

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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