Download Files:
iRucaparib-AP6
Price range: 730 CAD through 3,776 CAD
Products Details
Product Description
– iRucaparib-AP6, a non-trapping PARP1 degrader, blocks both the catalytic activity and scaffolding effects of PARP1. iRucaparib-AP6 is a highly efficient and specific PARP1 degrader based on Rucaparib by using the PROTAC approach.
Web ID
– T13737
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C46H55FN6O11
References
– Wang S, et al. Uncoupling of PARP1 trapping and inhibition using selective PARP1 degradation.Nat Chem Biol. 2019 Dec;15(12):1223-1231.
CAS Number
– 2410557-00-3
Molecular Weight
– C46H55FN6O11
SMILES
– O=C1NCCC2=C(NC3=CC(F)=CC1=C32)C4=CC=C(C=C4)CN(C)CCOCCOCCOCCOCCOCCOCCNC5=CC=CC=6C(=O)N(C(=O)C56)C7C(=O)NC(=O)CC7
Target
– Others
Pathway
– PROTAC
Product type
– PROTAC
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
Related Products
1000 in stock
1000 in stock
1000 in stock
