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GRK2-IN-1 hydrochloride (2055990-90-2 free base)
Price range: 3,872 CAD through 6,880 CAD
Products Details
Product Description
– GRKs-IN-1 hydrochloride has remarkable potency against and selectivity for G protein-coupled receptor kinase 2 GRK2 (IC50: 130 nM) and GRK5 (IC50: 7.1 μM).
Web ID
– T13714L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C24H26ClFN4O4
References
– Waldschmidt HV, et al. Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2Inhibitors Based on Paroxetine. J Med Chem. 2017 Apr 13;60(7):3052-3069.
Molecular Weight
– C24H26ClFN4O4
SMILES
– FC1=C(C(NCC2=NNC=C2)=O)C=C([C@H]3[C@H](COC4=CC=C(OCO5)C5=C4)CNCC3)C=C1.[H]Cl
Target
– Aminopeptidase|||Topoisomerase|||Mitophagy|||HIV Protease|||Autophagy|||Apoptosis|||NF-κB|||Endogenous Metabolite
Pathway
– GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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