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Products Details
Product Description
– MB-VC-MGBA is a agent-linker conjugate for ADC with potent antitumor activity by using MGBA (minor-groove-binding DNA-alkylating agent), linked via the ADC linker MB-VC[1].
Web ID
– HY-136289
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C56H65ClN12O10
References
– [1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
CAS Number
– 932744-62-2
Molecular Weight
– 1101.64
SMILES
– ClC[C@H](C1)C(C2=CC=CC=C2C(OC(N(CC3)CCN3C)=O)=C4)=C4N1C(C5=CC6=CC(NC(C(C=C7)=CC=C7NC([C@H](CCCNC(N)=O)NC([C@H](C(C)C)NCCNC(CCCN(C8=O)C(C=C8)=O)=O)=O)=O)=O)=CC=C6N5)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Duocarmycins
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
