Kinesore

SKU T15663-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 58 CAD through 877 CAD

Products Details

Product Description

– Kinesore is a cell-permeable small molecule modulator that binds primarily to the microtubule motor protein kinesin-1, thereby inhibiting the interaction between KLC2 (kinesin light chain 2) and SKIP (SKIP protein), and thus regulating the structure of the microtubule network to influence cytoskeletal organization and dynamics.

Web ID

– T15663

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C20H16Br2N4O4

References

– Randall TS, et al. A small-molecule activator of kinesin-1 drives remodeling of the microtubule network. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13738-13743.

CAS Number

– 363571-83-9

Molecular Weight

– C20H16Br2N4O4

Compound Purity

– 0.9724

SMILES

– O=C(C1=CC(Br)=C(C(Br)=C1)O)NN=CC2=C(C)N(C3=CC([N+]([O-])=O)=CC=C3)C(C)=C2

Target

– GPCR

Pathway

– Cytoskeletal Signaling

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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