IU1-47

SKU T15604-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 48 CAD through 1,712 CAD

Products Details

Product Description

– IU1-47 is an effective and specific USP14 inhibitor (IC50: 0.6 μM). IU1-47 causes tau elimination in cultured neurons. IU1-47 inhibits IsoT/USP5 (IC50: 20 μM).

Web ID

– T15604

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C19H23ClN2O

References

– Boselli M, et al. An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons. J Biol Chem. 2017 Nov 24;292(47):19209-19225.

CAS Number

– 670270-31-2

Molecular Weight

– C19H23ClN2O

Compound Purity

– 0.9955

SMILES

– Cc1cc(C(=O)CN2CCCCC2)c(C)n1-c1ccc(Cl)cc1

Target

– Drug Metabolite

Pathway

– Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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