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Pomalidomide 4′-alkylC5-acid
$130 – $370
Products Details
Product Description
– Pomalidomide 4′-alkylC5-acid (Example 3) is an E3 ligase ligand-linker conjugate containing a Pomalidomide (HY-10984) based cereblon (CRBN) ligand and a linker. Pomalidomide 4′-alkylC5-acid can be used in the synthesis of PROTAC[1].
Web ID
– HY-130737
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C19H21N3O6
References
– [1]Jian Jin, et al. Compositions and methods for treating cdk4/6-mediated cancer. Patent WO2018106870A1.
CAS Number
– 2225940-49-6
Molecular Weight
– 387.39
Compound Purity
– 98.78
SMILES
– O=C(O)CCCCCNC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– E3 Ligase Ligand-Linker Conjugates
Isoform
– Cereblon
Pathway
– PROTAC
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
