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Products Details
Product Description
– Mp-polymer ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-128970
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C129H220N20O52S2
References
– [1]Samantha Congreve, et al. Antibody drug conjugates (ADC) Current status and mapping of ADC:s in clinical programs.
Molecular Weight
– 2947.36
SMILES
– O=C(N1CCC(NCCOCCOCCC(NCCNC(CCNC(OCC(OCCC(CO)OC(CO)OCCC(CO)OC(COC(NCCC(O)=O)=O)OCCC(CO)OC(COC(NCCC(NCCNC(CCOCCOCCNC(CCN2C(CC(C2=O)SCC(N)C(O)=O)=O)=O)=O)=O)=O)OCCC(CO)OC(COC(NCCC(N[C@H](C(OCCCNC([C@@H](NC([C@@H]([C@H]([C@@H]3N(CCC3)C(C[C@H]([C@H]([C@H](CC)C)N(C([C@@H](NC([C@H](C(C)C)N(C)C)=O)C(C)C)=O)C)OC)=O)OC)C)=O)CC4=CC=CC=C4)=O)=O)C)=O)=O)OC)OC(CO)CC)=O)=O)=O)=O)C(CC1=O)SC
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Drug-Linker Conjugates for ADC
Isoform
– Non-cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
