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PI3K/mTOR Inhibitor-2
Price range: 85 CAD through 1,579 CAD
Products Details
Product Description
– PI3K/mTOR Inhibitor-2 is a potent pan inhibitor of PI3K and mTOR with IC50s of 3.4, 34, 16.1, and 4.7 nM for PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and mTOR, respectively. PI3K/mTOR Inhibitor-2 demonstrates antitumor activity.
Web ID
– T12459
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C20H13ClF2N4O4S
References
– Yu T, et al. Discovery of Pyridopyrimidinones as Potent and Orally Active Dual Inhibitors of PI3K/mTOR. ACS Med Chem Lett. 2018 Feb 27;9(3):256-261.
CAS Number
– 1848242-58-9
Molecular Weight
– C20H13ClF2N4O4S
Compound Purity
– 0.9616
SMILES
– COc1ncc(cc1NS(=O)(=O)c1ccc(F)cc1F)-c1ccc2ncc(Cl)c(=O)n2c1
Target
– CDK
Pathway
– PI3K/Akt/mTOR signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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