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Ned 19
Price range: 93 CAD through 2,448 CAD
Products Details
Product Description
– Ned 19, a selective membrane-permeant non-competitive antagonist of NAADP, strongly inhibits tumor growth, vascularization, and lung metastases in mice.
Web ID
– T12205
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H31FN4O3
Citations
– 1. Huang Y, Shao M, Teng X, et al.Inhibition of CD38 enzymatic activity enhances CAR-T cell immune-therapeutic efficacy by repressing glycolytic metabolism.Cell Reports Medicine.2024
References
– Rosen D, et al. Analogues of the nicotinic acid adenine dinucleotide phosphate (NAADP) antagonistNed-19 indicate two binding sites on the NAADP receptor. J Biol Chem. 2009 Dec 11;284(50):34930-4.
CAS Number
– 874374-25-1
Molecular Weight
– C30H31FN4O3
Compound Purity
– 0.9855
SMILES
– C(O)(=O)C1CC2=C(C(N1)C3=CC(CN4CCN(CC4)C5=C(F)C=CC=C5)=C(OC)C=C3)NC=6C2=CC=CC6
Pathway
– Membrane transporter/Ion channel|||Metabolism
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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