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Products Details
Product Description
– ML218 hydrochloride is a selective and orally active T-type Ca2+ channels (Cav3.1, Cav3.2, Cav3.3) inhibitor (Cav3.2 and Cav3.3 with IC50s of 310 nM and 270 nM , respectively).
Web ID
– T12076
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C19H27Cl3N2O
References
– Xiang Z, et al. The Discovery and Characterization of ML218: A Novel, Centrally Active T-Type Calcium Channel Inhibitor with Robust Effects in STN Neurons and in a Rodent Model of Parkinson’s Disease. ACS Chem Neurosci. 2011 Dec 21;2(12):730-742.
CAS Number
– 2319922-08-0
Molecular Weight
– C19H27Cl3N2O
SMILES
– C(NC(=O)C1=CC(Cl)=CC(Cl)=C1)[C@H]2[C@]3([C@@]2(CN(CCC(C)(C)C)C3)[H])[H].Cl
Pathway
– Others
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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