Amsacrine

SKU T1206-1 mL * 10 mM (in DMSO) Category Small Compound Brand: TargetMol

Price range: 46 CAD through 88 CAD

Size

1 mL * 10 mM (in DMSO)10 mg 25 mg

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Product Description

– Amsacrine (AMSA) (mAMSA) an antineoplastic agent which can intercalate into the DNA of tumor cells. Amsacrine also expresses topoisomerase inhibitor activity, specifically inhibiting topoisomerase II.

Web ID

– T1206

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C21H19N3O3S

Citations

– 1. Fu W, Li X, Lu X, et al. A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells. Cell Death & Disease. 2017, 8(10): e3086-e3086

References

– Thomas D, et al. Inhibition of cardiac HERG currents by the DNA topoisomerase II inhibitor amsacrine: mode of action. Br J Pharmacol. 2004 Jun;142(3):485-94.

CAS Number

– 51264-14-3

Molecular Weight

– C21H19N3O3S

Compound Purity

– 0.992

SMILES

– N(C=1C2=C(N=C3C1C=CC=C3)C=CC=C2)C4=C(OC)C=C(NS(C)(=O)=O)C=C4

Target

– NMDAR|||iGluR

Pathway

– Autophagy|||DNA Damage/DNA Repair|||Membrane transporter/Ion channel

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

Amsacrine

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