LS-102
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LS-102

SKU T11879-1 mL * 10 mM (in DMSO) Category Brand:

Price range: 80 CAD through 845 CAD

Products Details

Product Description

– LS-102 is a selective inhibitor of the E3 ligase synoviolin (Syvn1), an astragaloside IV derivative, which attenuates myocardial ischemia/reperfusion injury by inhibiting mitochondrial fission.LS-102 inhibits Syvn1 auto-ubiquitylation, which ameliorates amyloidazole-induced slowing of the heart rate, and is useful for studying cardiovascular diseases.

Web ID

– T11879

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C24H36N8O

References

– Yagishita N, et al. RING-finger type E3 ubiquitin ligase inhibitors as novel candidates for the treatment of rheumatoidarthritis. Int J Mol Med. 2012 Dec;30(6):1281-6.

CAS Number

– 1456891-34-1

Molecular Weight

– C24H36N8O

SMILES

– CCNCCN(CC)c1nc(N[C@@H](C)C2CCCCC2)nc(Nc2ccc3ncoc3c2)n1

Target

– Apoptosis|||COX

Pathway

– PROTAC

Product type

– Small Compound

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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