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Epertinib
Price range: 2,176 CAD through 4,000 CAD
Products Details
Product Description
– Epertinib is a reversible and selective tyrosine kinase inhibitor of EGFR, HER2, and HER4 (IC50s: 1.48 nM, 7.15 nM, and 2.49 nM). It displays a strong antitumor activity.
Web ID
– T11213L
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C30H27ClFN5O3
References
– Tanaka H, et al. Preclinical antitumor activity of S-222611, an oral reversible tyrosine kinase inhibitor of epidermal growth factor receptor and human epidermal growth factor receptor 2. Cancer Sci. 2014 Aug;105(8):1040-8.
CAS Number
– 908305-13-5
Molecular Weight
– C30H27ClFN5O3
SMILES
– N(C=1C2=C(C=CC(C(=NOC[C@H]3COCCN3)C#CC)=C2)N=CN1)C4=CC(Cl)=C(OCC5=CC(F)=CC=C5)C=C4
Target
– PKC
Pathway
– Tyrosine Kinase/Adaptors|||Angiogenesis|||JAK/STAT signaling
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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