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Dooku1
Price range: 61 CAD through 1,237 CAD
Products Details
Product Description
– Dooku1 is an analog of Yoda1 and a selective antagonist of endogenous Piezo1 channels. Dooku1 inhibits Ca2+ entry induced by 2μMYoda1 with IC50 values of 1.3μM (in HEK 293 cells) and 1.5μM (in HUVEC). Dooku1 inhibits Yoda1-induced aortic relaxation.
Web ID
– T11076
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C13H9Cl2N3OS
References
– Evans EL, et al. Yoda1 analogue (Dooku1) which antagonizes Yoda1-evoked activation of Piezo1 and aortic relaxation. Br J Pharmacol. 2018 May;175(10):1744-1759.
CAS Number
– 2253744-54-4
Molecular Weight
– C13H9Cl2N3OS
Compound Purity
– 0.994
SMILES
– Clc1cccc(Cl)c1CSc1nnc(o1)-c1ccc[nH]1
Target
– Cholecystokinin Receptor
Pathway
– Membrane transporter/Ion channel
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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