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PPOH
$85 – $780
Products Details
Product Description
– PPOH, a fatty acid derivative, is a selective cyclooxygenase (COX) inhibitor that inhibits arachidonic acid cyclooxygenase activity in renal cortical microsomes. In addition, PPOH acts on CYP4A2 and CYP4A3 with the IC50 values of 22 μM and 6.5 μM, respectively[1]. PPOH is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Web ID
– HY-119647
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Metabolism-sugar/lipid metabolism
Molecular Formula
– C15H18O3
References
– [1]Melissa A VanAlstine, et al. Effects of acetylenic epoxygenase inhibitors on recombinant cytochrome p450s. Drug Metab Dispos. 2011 Jul;39(7):1221-6.
CAS Number
– 206052-01-9
Molecular Weight
– 246.30
Compound Purity
– 99.87
SMILES
– C#CCOC1=CC=CC=C1CCCCCC(O)=O
Clinical Information
– No Development Reported
Research Area
– Others
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– COX;Cytochrome P450
Pathway
– Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
