CCR7 Ligand 1
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CCR7 Ligand 1

SKU T10716-2 mg Category Brand:

Price range: 3,085 CAD through 16,320 CAD

Products Details

Product Description

– CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.

Web ID

– T10716

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H29N5O5S

References

– Jaeger K, et al. Structural Basis for Allosteric Ligand Recognition in the Human CC Chemokine Receptor 7. Cell. 2019 Aug 22;178(5):1222-1230.e10.

CAS Number

– 681514-83-0

Molecular Weight

– C22H29N5O5S

SMILES

– CN(C)C(=O)c1c(C)ccc(NC2=NS(=O)(=O)N=C2N[C@@H](c2ccc(C)o2)C(C)(C)C)c1O

Target

– Others

Pathway

– Others

Product type

– PROTAC

Booklet

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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