β3-AR agonist 1

SKU T10523-25 mg Category Brand:

Price range: 3,152 CAD through 5,440 CAD

Products Details

Product Description

– β3-AR agonist 1 is a highly selective, and orally available agonist of β3-adrenergic receptor (EC50: 18 nM), being inactive to β1-, β2-, and α1A-AR (β1/β3, β2/β3, and α1A/β3>556-fold).

Web ID

– T10523

Storage Temperature

– -20℃

Shipping

– Blue Ice

Molecular Formula

– C22H28N4O4S

References

– Wada Y, et al. Discovery of Novel Indazole Derivatives as Orally Available β3-Adrenergic Receptor Agonists Lacking Off-Target-Based Cardiovascular Side Effects. J Med Chem. 2017 Apr 27;60(8):3252-3265.

CAS Number

– 1283125-73-4

Molecular Weight

– C22H28N4O4S

SMILES

– CC=1C=2C(=CC(OCCNC[C@H](O)C3=CC(NS(=O)(=O)C4CCC4)=CC=C3)=CC2)NN1

Target

– Others

Pathway

– Others

Product type

– Small Compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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