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Products Details
Product Description
– ALK-IN-6 is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK, IC50s: 71 nM, 18.72 nM, and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L).
Web ID
– T10284
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C26H29ClD3N5O3S
References
– Das D, et al. Design, synthesis of orally bioavailable novel anaplastic lymphoma kinase (ALK) inhibitor diphenylaminopyrimidine analogs and efficacy study on NCI-H2228 xenografts mice model. Bioorg Med Chem Lett. 2019 Jun 15;29(12):1514-1517.
CAS Number
– 2055821-33-3
Molecular Weight
– C26H29ClD3N5O3S
SMILES
– N(C1=C(S(C(C)C)(=O)=O)C=CC=C1)C2=NC(NC3=C(OC([2H])([2H])[2H])C=C(C(C)=C3)C4CCNCC4)=NC=C2Cl
Target
– Others
Product type
– Isotope products
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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