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H4 Receptor antagonist 1
$90 – $850
Products Details
Product Description
– H4 Receptor antagonist 1 is a potent and selective histamine H4 receptor inverse agonist, with an IC50 of 19 nM.
Web ID
– HY-114025
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H17ClN4O
References
– [1]Cramp S, et al. Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonists. Bioorg Med Chem Lett. 2010 Apr 15;20(8):2516-9.
CAS Number
– 848217-00-5
Molecular Weight
– 316.79
Compound Purity
– 99.66
SMILES
– CN1CCN(C2=C(OC3=CC=C(Cl)C=C34)C4=NC(C)=N2)CC1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease; Endocrinology
Solubility
– DMSO : 10 mg/mL (ultrasonic)
Target
– Histamine Receptor
Isoform
– H4 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
