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Clozapine
Price range: 48 CAD through 757 CAD
Products Details
Product Description
– Clozapine (HF 1854) is a tricylic dibenzodiazepine, classified as an atypical antipsychotic agent. It binds several types of central nervous system receptors, and displays a unique pharmacological profile. Clozapine is a serotonin antagonist, with strong binding to 5-HT 2A/2C receptor subtype. It also displays strong affinity to several dopaminergic receptors, but shows only weak antagonism at the dopamine D2 receptor, a receptor commonly thought to modulate neuroleptic activity.
Web ID
– T0455
Storage Temperature
– -20℃
Shipping
– Blue Ice
Molecular Formula
– C18H19ClN4
Citations
– 1. Xu Z, Guo L, Yu J, et al.Ligand recognition and G protein coupling of trace amine receptor TAAR1.Nature.2023: 1-3.
References
– Robertson GS, et al. Neuroscience, 1992, 46(2), 315-328.
CAS Number
– 5786-21-0
Molecular Weight
– C18H19ClN4
Compound Purity
– 0.9993
SMILES
– CN1CCN(CC1)C1=NC2=C(NC3=C1C=CC=C3)C=CC(Cl)=C2
Target
– Phosphatase
Pathway
– Neuroscience|||GPCR/G Protein
Product type
– Small Compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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