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β-D-glucuronide-pNP-carbonate
$500 – $914
Products Details
Product Description
– β-D-glucuronide-pNP-carbonate is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Web ID
– HY-136329
Storage Temperature
– -20°C, 3 years (Powder)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C45H43N3O18
References
– [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
CAS Number
– 894095-98-8
Molecular Weight
– 913.83
Compound Purity
– 99.44
SMILES
– O=C(NCCC(NC(C=C1COC(OC(C=C2)=CC=C2[N+]([O-])=O)=O)=C(C=C1)O[C@H](O[C@@H]3C(OC)=O)[C@@H]([C@H]([C@@H]3OC(C)=O)OC(C)=O)OC(C)=O)=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– ADC Linker
Isoform
– Cleavable Linker;Glycosidase Cleavable Linker
Pathway
– Antibody-drug Conjugate/ADC Related
Product type
– ADC Related
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
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