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Products Details
Product Description
– β-catenin-IN-4 (Compound 39) is a β-catenin inhibitor with a Ki of 0.64 μM. β-catenin-IN-4 reduces the protein expression levels of cyclin D1 and c-Myc[1].
Web ID
– HY-147651
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C38H33ClF3N5O9
References
– [1]McCoy MA, et al. Biophysical Survey of Small-Molecule β-Catenin Inhibitors: A Cautionary Tale. J Med Chem. 2022 May 26;65(10):7246-7261.
CAS Number
– 2353536-67-9
Molecular Weight
– 796.14
SMILES
– O=C(N[C@H](C(NC1=CC=C(C=C1)OC(F)(F)F)=O)CCC(O)=O)[C@@H](NC([C@@H](NC(C2=CC3=C(N2)C=CC(Cl)=C3)=O)CC4=CC=C5C=CC=CC5=C4)=O)CC(O)=O
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– β-catenin
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
