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β-Anhydroicaritin
$60 – $180
Products Details
Product Description
– β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties[1]. β-Anhydroicaritin ameliorates the degradation of periodontal tissue and inhibits the synthesis and secretion of TNF-α and MMP-3 in diabetic rats[2]. β-Anhydroicaritin decreases the overproduction of NO, IL-10, TNF-α, MCP-1 and IL-6 in inperitonitis mice. β-Anhydroicaritin inhibits the elevation of intracellular Ca2+, and markedly decreases iNOS protein expression[3].
Web ID
– HY-N1940
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C21H20O6
References
– [1]Nguyen VS, et al. Synthesis of Icaritin and β-anhydroicaritin Mannich Base Derivatives and Their Cytotoxic Activities on Three Human Cancer Cell Lines. Anticancer Agents Med Chem. 2017;17(1):137-142|[2]Wu Y, et al. Effect of β-anhydroicaritin on the expression levels of tumor necrosis factor-α and matrix metalloproteinase-3 in periodontal tissue of diabetic rats. Mol Med Rep. 2015 Aug;12(2):1829-37.|[3]Lai X, et al. Protective effect of anhydroicaritin against peritonitis in mice. Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi. 2013 Oct;29(10):1036-9.
CAS Number
– 38226-86-7
Molecular Weight
– 368.38
Compound Purity
– 99.09
SMILES
– O=C1C2=C(O)C=C3C(CCC(C)(C)O3)=C2OC(C4=CC=C(OC)C=C4)=C1O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– DMSO : 8.33 mg/mL (ultrasonic)
Target
– Interleukin Related;MMP;TNF Receptor
Isoform
– CD40;IL-10;IL-6;MMP-3
Pathway
– Apoptosis;Immunology/Inflammation;Metabolic Enzyme/Protease
Product type
– Natural Products
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
