β-Aminopropionitrile

$55$61

Products Details

Product Description

– β-Aminopropionitrile (BAPN) is a specific, irreversible and orally active lysyl oxidase (LOX) inhibitor. β-Aminopropionitrile targets the active site of LOX or LOXL isoenzymes[1][2].

Web ID

– HY-Y1750

Storage Temperature

– -20°C (Powder, protect from light, stored under nitrogen)

Shipping

– Blue Ice

Applications

– Cancer-programmed cell death

Molecular Formula

– C3H6N2

References

– [1]Ren W, et al. β-Aminopropionitrile monofumarate induces thoracic aortic dissection in C57BL/6 mice. Sci Rep. 2016 Jun 22;6:28149.|[2]Miana M, et al. The lysyl oxidase inhibitor β-aminopropionitrile reduces body weight gain and improves the metabolic profile in diet-induced obesity in rats. Dis Model Mech. 2015 Jun;8(6):543-51.|[3]Yang X, et al. Inactivation of lysyl oxidase by β-aminopropionitrile inhibits hypoxia-induced invasion and migration of cervical cancer cells. Oncol Rep. 2013 Feb;29(2):541-8.

CAS Number

– 151-18-8

Molecular Weight

– 70.09

Compound Purity

– 99.99

SMILES

– N#CCCN

Clinical Information

– No Development Reported

Research Area

– Cancer, Metabolic Disease

Solubility

– DMSO : 100 mg/mL (ultrasonic)|H2O : 50 mg/mL (ultrasonic)

Target

– Endogenous Metabolite, Monoamine Oxidase

Isoform

– Human Endogenous Metabolite

Pathway

– Metabolic Enzyme/Protease, Neuronal Signaling

Product type

– Natural Products

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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