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Products Details
Product Description
– αβ-Tubulin-IN-1 is a potent and orally active αβ-Tubulin inhibitor. αβ-Tubulin-IN-1 induces cell cycle arrest at G2/M and efficient apoptosis. αβ-Tubulin-IN-1 inhibits tumor cell migration and Metastasis. αβ-Tubulin-IN-1 shows significant antitumor efficacy in a dose dependent manner[1].
Web ID
– HY-144132
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C25H19N3O3
References
– [1]Li Y, et al. Structure-Based Design and Synthesis of N-Substituted 3-Amino-β-Carboline Derivatives as Potent αβ-Tubulin Degradation Agents. J Med Chem. 2022 Feb 10;65(3):2675-2693.
CAS Number
– 2478584-74-4
Molecular Weight
– 409.44
SMILES
– C(N1)(C=NC(NCC2=CC=CC(OC3=CC=C(OCO4)C4=C3)=C2)=C5)=C5C6=C1C=CC=C6
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Apoptosis;Microtubule/Tubulin
Pathway
– Apoptosis;Cell Cycle/DNA Damage;Cytoskeleton
Product type
– Reference compound
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