Download Files:
α5IA
$80 – $160
Products Details
Product Description
– α5IA (L-822179) is a selective α5 GABAA receptor inverse agonist with neuroprotective potential[1].
Web ID
– HY-116622
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Molecular Formula
– C17H14N8O2
References
– [1]Chitra Vinnakota, et al. An 5 GABAA Receptor Inverse Agonist, 5IA, Attenuates Amyloid Beta-Induced Neuronal Death in Mouse Hippocampal Cultures. Int J Mol Sci. 2020 May 6;21(9):3284. |[2]Arnaud Duchon, et al. Long-lasting correction of in vivo LTP and cognitive deficits of mice modelling Down syndrome with an α5-selective GABAA inverse agonist. Br J Pharmacol. 2020 Mar;177(5):1106-1118.
CAS Number
– 215874-86-5
Molecular Weight
– 362.35
Compound Purity
– 97.0
SMILES
– CN1N=NC(COC(C2=C3C=CC=C2)=NN4C3=NN=C4C5=NOC(C)=C5)=C1
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– GABA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
