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Products Details
Product Description
– α-Synuclein inhibitor 8 is an active inhibitor of α-Synuclein with an IC50 value of 2.5 µM. α-Synuclein inhibitor 8 has highly inhibition on the aggregation and disaggregation of α-Synuclein fibers. α-Synuclein inhibitor 8 reduces the formation of inclusions in neurons that can repairs damage neurons and improves Parkinson’s disease (PD)-like symptoms. α-Synuclein inhibitor 8 has high antioxidant activity and low cytotoxicity[1].
Web ID
– HY-152552
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C24H20N2O6
References
– [1]Lü MH, et al. Hybrids of polyphenolic/quinone acids, the potential preventive and therapeutic drugs for PD: Disaggregate α-Syn fibrils, inhibit inclusions, and repair damaged neurons in mice. Eur J Med Chem. 2023 Jan 18;249:115122.
CAS Number
– 2883627-64-1
Molecular Weight
– 432.43
SMILES
– OC1=CC=C(O)C=C1/C=C/C(NC2=CC=C(NC(/C=C/C3=CC(O)=CC=C3O)=O)C=C2)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– α-synuclein
Pathway
– Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
