α-Synuclein inhibitor 5

SKU HY-147667-Get quote Category Tags ,

Products Details

Product Description

– α-Synuclein inhibitor 5 (compound 4aa) is a potent and BBB-penetrated inhibitor of α-Synuclein (α-Syn) aggregation, with an IC50 of 1.22 μM and inhibition ratio at 30 μM of 94.3%[1].

Web ID

– HY-147667

Shipping

– Room temperature

Applications

– Neuroscience-Neurodegeneration

Molecular Formula

– C20H18N2O6S

References

– [1]Chen L, et al. Amide derivatives of Gallic acid: Design, synthesis and evaluation of inhibitory activities against in vitro α-synuclein aggregation. Bioorg Med Chem. 2020 Aug 1;28(15):115596.

CAS Number

– 2489813-11-6

Molecular Weight

– 414.43

SMILES

– CC1=CC=C(C=C1)S(=O)(NC2=CC=C(C=C2)NC(C3=CC(O)=C(C(O)=C3)O)=O)=O

Clinical Information

– No Development Reported

Research Area

– Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Others

Pathway

– Others

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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