Download Files:
Zuclopenthixol-d4 (succinate salt)
SKU
HY-A0163S-1 mg
Category Isotope-Labeled Compounds
Tags Dopamine Receptor, GPCR/G Protein;Neuronal Signaling, Neurological Disease
$790 – $1,900
Products Details
Product Description
– Zuclopenthixol-d4 (succinate) is the deuterium labeled Zuclopenthixol. Zuclopenthixol is a thioxanthene derivative which acts as a mixed dopamine D1/D2 receptor antagonist[1][2].
Web ID
– HY-A0163S
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C26H27D4ClN2O5S
References
– [1]Manzaneque JM, et al. An ethopharmacological assessment of the effects of zuclopenthixol on agonistic interactions in male mice. Methods Find Exp Clin Pharmacol. 1999 Jan-Feb;21(1):11-5.|[2]Khalifa AE, et al. Pro-oxidant activity of zuclopenthixol in vivo: differential effect of the drug on brain oxidative status of scopolamine-treated rats. Hum Exp Toxicol. 2004 Aug;23(9):439-45.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.
CAS Number
– 1246833-97-5
Molecular Weight
– 523.08
SMILES
– C(CC(O)=O)C(O)=O.C(CCN1CCN(C(C(O)([2H])[2H])([2H])[2H])CC1)=C2C=3C(SC=4C2=CC=CC4)=CC=C(Cl)C3
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Isoform
– D2 Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Isotope-Labeled Compounds
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.