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Zolertine (hydrochloride)
SKU
HY-123368-Get quote
Category Reference compound
Tags Adrenergic Receptor, Cardiovascular Disease, GPCR/G Protein;Neuronal Signaling
Products Details
Product Description
– Zolertine hydrochloride is an α-adrenoceptor antagonist with a pKi of 6.81 in rat liver (α1B-adrenoceptors) and 6.35 in rabbit liver (α1A-adrenoceptors) membranes[1].
Web ID
– HY-123368
Shipping
– Room temperature
Molecular Formula
– C13H19ClN6
References
– [1]Ibarra M, et al. The alpha-adrenoceptor antagonist, zolertine, inhibits alpha1D- and alpha1A-adrenoceptor-mediated vasoconstriction in vitro. J Auton Pharmacol. 2000 Jun;20(3):139-45.
CAS Number
– 7241-94-3
Molecular Weight
– 294.78
SMILES
– [H]Cl.N1(CCN(CC1)CCC2=NN=NN2)C3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– 10 mM in DMSO
Target
– Adrenergic Receptor
Isoform
– α adrenergic receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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