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Zofenopril
SKU
HY-108321-5 mg
Category Reference compound
Tags Angiotensin-converting Enzyme (ACE), Metabolic Enzyme/Protease, Neurological Disease
$192
Only 1000 item(s) left in stock.
Products Details
Product Description
– Zofenopril is an angiotensin-converting enzyme (ACE) inhibitor with an IC50 of 81 μM.
Web ID
– HY-108321
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C22H23NO4S2
References
– [1]Lin CJ, et al. Competitive inhibition of glycylsarcosine transport by enalapril in rabbit renal brush border membrane vesicles: interaction of ACE inhibitors with high-affinity H+/peptide symporter. Pharm Res. 1999 May;16(5):609-15.|[2]Sarro GD, et al. Fosinopril and zofenopril, two angiotensin-converting enzyme (ACE) inhibitors, potentiate the anticonvulsant activity of antiepileptic drugs against audiogenic seizures in DBA/2 mice. Pharmacol Res. 2012 Mar;65(3):285-96.
CAS Number
– 81872-10-8
Molecular Weight
– 429.55
Compound Purity
– 98.81
SMILES
– O=C(O)[C@H]1N(C([C@H](C)CSC(C2=CC=CC=C2)=O)=O)C[C@@H](SC3=CC=CC=C3)C1
Clinical Information
– Launched
Research Area
– Neurological Disease
Solubility
– DMSO : 5 mg/mL (ultrasonic)
Target
– Angiotensin-converting Enzyme (ACE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.