Download Files:
Products Details
Product Description
– ZM514 is a potent CD73 inhibitor with IC50s of 1.39 μM and 14.65 μM for hCD73 and mCD73, respectively. ZM514 has low cytotoxicity. ZM514 can be used for researching anticancer[1].
Web ID
– HY-146759
Shipping
– Room temperature
Applications
– Cancer-programmed cell death
Molecular Formula
– C36H57NO4
References
– [1]Zhang Y, et al. Discovery and optimization of betulinic acid derivatives as novel potent CD73 inhibitors. Bioorg Med Chem. 2022;59:116672.
Molecular Weight
– 567.84
SMILES
– [H][C@@]12CC[C@@]3([C@](CC[C@@]4([C@]5([C@@H](CC[C@@]5(CC[C@]43C)C(O)=O)C(C)=C)[H])[H])([C@]1(CC[C@@H](C2(C)C)OC(N6CCCCC6)=O)C)[H])C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– CD73
Pathway
– Immunology/Inflammation
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
