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ZINC13466751
$250 – $1,700
Products Details
Product Description
– ZINC13466751 is a potent inhibitor of HIF-1α/von Hippel-Lindau interaction with an IC50 of 2.0 µM[1].
Web ID
– HY-101028
Storage Temperature
– -20°C (Powder, stored under nitrogen)
Shipping
– Blue Ice
Applications
– Cancer-programmed cell death
Molecular Formula
– C20H21N5O2
References
– [1]Xue X, et al. Discovery of novel inhibitors disrupting HIF-1α/von Hippel-Lindau interaction through shape-based screening and cascade docking. PeerJ. 2016 Dec 15;4:e2757.
CAS Number
– 117953-17-0
Molecular Weight
– 363.41
Compound Purity
– 98.62
SMILES
– O=C(N(C1=CC=CC=C1)N=C/2C)C2=N/NC3=CC=C(N4CCOCC4)C=C3
Clinical Information
– No Development Reported
Research Area
– Cancer; Cardiovascular Disease
Solubility
– DMSO : 50 mg/mL (ultrasonic)
Target
– HIF/HIF Prolyl-Hydroxylase
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
