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Zimelidine
SKU
HY-118835-Get quote
Category Reference compound
Tags 5-HT Receptor;Serotonin Transporter, GPCR/G Protein;Neuronal Signaling, Neurological Disease
Products Details
Product Description
– Zimelidine is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine is an antidepressant[1][2][3][4].
Web ID
– HY-118835
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H17BrN2
References
– [1]Heel RC, et al. Zimelidine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1982 Sep;24(3):169-206.|[2]Blier P, et al. Electrophysiological investigations on the effect of repeated zimelidine administration on serotonergic neurotransmission in the rat. J Neurosci. 1983 Jun;3(6):1270-8.|[3]Ozdemir E, et al. Zimelidine attenuates the development of tolerance to morphine-induced antinociception. Indian J Pharmacol. 2012 Mar;44(2):215-8.|[4]Scopinho AA, et al. Medial amygdaloid nucleus 5-HTâ‚‚c receptors are involved in the hypophagic effect caused by zimelidine in rats. Neuropharmacology. 2012 Aug;63(2):301-9.
CAS Number
– 56775-88-3
Molecular Weight
– 317.22
SMILES
– CN(C/C=C(C1=CC=CN=C1)/C2=CC=C(C=C2)Br)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Serotonin Transporter
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.