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Products Details
Product Description
– Zimelidine is a potent and selective inhibitor of serotonin 5-HT uptake and SERT. Zimelidine is an antidepressant[1][2][3][4].
Web ID
– HY-118835
Shipping
– Room temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H17BrN2
References
– [1]Heel RC, et al. Zimelidine: a review of its pharmacological properties and therapeutic efficacy in depressive illness. Drugs. 1982 Sep;24(3):169-206.|[2]Blier P, et al. Electrophysiological investigations on the effect of repeated zimelidine administration on serotonergic neurotransmission in the rat. J Neurosci. 1983 Jun;3(6):1270-8.|[3]Ozdemir E, et al. Zimelidine attenuates the development of tolerance to morphine-induced antinociception. Indian J Pharmacol. 2012 Mar;44(2):215-8.|[4]Scopinho AA, et al. Medial amygdaloid nucleus 5-HTâ‚‚c receptors are involved in the hypophagic effect caused by zimelidine in rats. Neuropharmacology. 2012 Aug;63(2):301-9.
CAS Number
– 56775-88-3
Molecular Weight
– 317.22
SMILES
– CN(C/C=C(C1=CC=CN=C1)/C2=CC=C(C=C2)Br)C
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– 5-HT Receptor;Serotonin Transporter
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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