Zileuton (sodium)

$38$228

Products Details

Product Description

– Zileuton sodium (A 64077 sodium) is a potent and selective inhibitor of 5-lipoxygenase, exhibiting inflammatory activities.

Web ID

– HY-14164A

Storage Temperature

– 4°C (Powder, sealed storage, away from moisture)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C11H11N2NaO2S

References

– [1]Kuvibidila S, et al. Hydroxyurea and Zileuton Differentially Modulate Cell Proliferation and Interleukin-2 Secretion by Murine Spleen Cells: Possible Implication on the Immune Function and Risk of Pain Crisis in Patients with Sickle Cell Disease. Ochsner|[2]Gounaris E, et al. Zileuton, 5-lipoxygenase inhibitor, acts as a chemopreventive agent in intestinal polyposis, by modulating polyp and systemic inflammation. PLoS One. 2015 Mar 6;10(3):e0121402|[3]Abueid L, et al. Inhibition of 5-lipoxygenase by zileuton in a rat model of myocardial infarction. Anatol J Cardiol. 2016 Nov 10

CAS Number

– 118569-21-4

Molecular Weight

– 258.27200928

Compound Purity

– 98.61

SMILES

– CC(N([O-])C(N)=O)C1=CC2=CC=CC=C2S1.[Na+]

Clinical Information

– Launched

Research Area

– Inflammation/Immunology; Cancer

Solubility

– 10 mM in DMSO

Target

– Lipoxygenase

Isoform

– 5-LOX

Pathway

– Metabolic Enzyme/Protease

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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