Products Details

Product Description

– ZIKV-IN-4 (compound 5b) is a low-cytotoxicity and acid-stable anti-ZIKV agent (EC50=3.49 μM). ZIKV-IN-4 effectively inhibits the activity of ZIKV NS5 MTase[1].

Web ID

– HY-151447

Shipping

– Room temperature

Applications

– COVID-19-anti-virus

Molecular Formula

– C33H37NO4

References

– [1]Qian W, et al. Discovery of dehydroandrographolide derivatives with C19 hindered ether as potent anti-ZIKV agents with inhibitory activities to MTase of ZIKV NS5. Eur J Med Chem. 2022 Aug 27;243:114710.

Molecular Weight

– 511.65

SMILES

– C=C(CC[C@]1([H])[C@@]/2(COC(C3=CC=CC=C3)C4=CC=CC=C4)C)[C@@H](/C=C/C5=CCOC5=O)[C@]1(C)CCC2=N/O

Clinical Information

– No Development Reported

Research Area

– Infection

Solubility

– 10 mM in DMSO

Target

– Virus Protease

Pathway

– Anti-infection

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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