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Products Details
Product Description
– ZEN-2759 is a potent BET (Bromodomain and Extra-Terminal Domain) inhibitor, with IC50 values of 0.23, 0.08 and 0.28 μM for BRD4(BD1), BRD4(BD2), and BRD4(BD1BD2), respectively[1].
Web ID
– HY-129201
Shipping
– Room temperature
Molecular Formula
– C17H16N2O2
References
– [1]Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain (BET) Inhibitors Targeting a Methionine. J Med Chem. 2018 Sep 27;61(18):8202-8211.
CAS Number
– 1616400-50-0
Molecular Weight
– 280.32
SMILES
– O=C1C=CC(C2=C(ON=C2C)C)=CN1CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– Epigenetic Reader Domain
Isoform
– BRD4
Pathway
– Epigenetics
Product type
– Reference compound
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