ZCZ011

$350$550

Products Details

Product Description

– ZCZ011 is a potent and brain penetrant cannabinoid 1 (CB1) receptor positive allosteric modulator. ZCZ011 potentiates binding of CP55,940 to the CB1 receptor, enhances anandamide (AEA)-stimulated GTPγS binding in mouse brain membranes. ZCZ011 increases β-arrestin recruitment and ERK phosphorylation in hCB1 cells. ZCZ011 can be used for researching neuropathic and inflammatory pain[1].

Web ID

– HY-118140

Storage Temperature

– -20°C, 3 years; 4°C, 2 years (Powder)

Shipping

– Room Temperature

Applications

– COVID-19-immunoregulation

Molecular Formula

– C21H18N2O2S

References

– [1]Ignatowska-Jankowska BM, et al. A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects. Neuropsychopharmacology. 2015;40(13):2948-2959.

CAS Number

– 1998197-39-9

Molecular Weight

– 362.44

Compound Purity

– 99.0

SMILES

– O=[N+](CC(C1=C(C2=CC=CC=C2)NC3=C1C=CC(C)=C3)C4=CC=CS4)[O-]

Clinical Information

– No Development Reported

Research Area

– Inflammation/Immunology; Neurological Disease

Solubility

– 10 mM in DMSO

Target

– Cannabinoid Receptor

Pathway

– GPCR/G Protein;Neuronal Signaling

Product type

– Reference compound

Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.

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