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Zagociguat
$300 – $2,250
Products Details
Product Description
– Zagociguat is the stimulator of soluble guanylate cyclase. Zagociguat increases nitric oxide (NO) signaling leading to an increase in cyclic guanosine monophosphate production. Zagociguat has the potential for the research of noncentral nervous system (CNS) disorders[1].
Web ID
– HY-145607
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Applications
– Neuroscience-Neuromodulation
Molecular Formula
– C16H10F4N6
References
– [1]Debra J. Wallace, et al. Accelerated Development of a Scalable Synthesis of CY6463, a CNS-Penetrant sGC Stimulator for the Treatment of Neurodegenerative Diseases. Org Process Res Dev. 2021;25(10):2288-2299.
CAS Number
– 2201048-82-8
Molecular Weight
– 362.28
Compound Purity
– 99.68
SMILES
– FC1=C(CC2=NC(C3=NN=C(C(F)(F)F)N3)=CN4C=CN=C24)C=CC=C1
Clinical Information
– No Development Reported
Research Area
– Cardiovascular Disease
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Guanylate Cyclase
Pathway
– GPCR/G Protein
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
