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Zabofloxacin (hydrochloride)
$690 – $5,650
Products Details
Product Description
– Zabofloxacin hydrochloride (DW-224a) is a potent and seletive inhibitor of the bacterial type II and IV topoisomerases. Zabofloxacin hydrochloride has excellent activity against gram-positive pathogens including Steptococcus aureus, Streptococcus pyogenes and S.pneumonia. Zabofloxacin hydrochloride is a novel fluoronaphthyridone quinolone that is considered as an alternative antibiotic for treatment of quinolone-susceptible (QSSP) and quinolone-resistant gonorrhea (QRSP)[1].
Web ID
– HY-106410A
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-anti-virus
Molecular Formula
– C19H21ClFN5O4
References
– [1]Park HS, et al. Antimicrobial Activity of Zabofloxacin against Clinically Isolated Streptococcus pneumoniae. Molecules. 2016 Nov 17;21(11). pii: E1562.
CAS Number
– 623574-00-5
Molecular Weight
– 437.85
Compound Purity
– 98.06
SMILES
– O=C(O)C1=CN(C2=NC(N(CC/34CNC4)CC3=NOC)=C(C=C2C1=O)F)C5CC5.[H]Cl
Clinical Information
– Phase 3
Research Area
– Infection
Solubility
– DMSO : 6.67 mg/mL (ultrasonic;warming;heat to 60°C)
Target
– Antibiotic;Bacterial;Topoisomerase
Isoform
– Quinolone;Topo I;Topo II
Pathway
– Anti-infection;Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
