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Z4P
$220 – $1,820
Products Details
Product Description
– Z4P is a BBB-permeable IRE1 inhibitor (IC50: 1.11 μM). Z4P inhibits Glioblastoma cell growth. Z4P prevents glioblastoma relapse when administered together with Temozolomide (HY-17364)[1].
Web ID
– HY-153773
Storage Temperature
– -20°C, 3 years; 4°C, 2 years (Powder)
Shipping
– Room Temperature
Molecular Formula
– C19H24N2O2
References
– [1]Pelizzari-Raymundo D, et al. A novel IRE1 kinase inhibitor for adjuvant glioblastoma treatment. iScience. 2023 Apr 24;26(5):106687.
CAS Number
– 2361760-87-2
Molecular Weight
– 312.41
Compound Purity
– 99.32
SMILES
– O=C(NC(CCC1=CC=C(C=C1)O)C)NC2=CC(C)=CC=C2C
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– 10 mM in DMSO
Target
– IRE1
Pathway
– Cell Cycle/DNA Damage
Product type
– Reference compound
Disclaimer: All products are for research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation.
