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Products Details
Product Description
– Z-Phe-Tyr(tBu)-diazomethylketone is a potent cathepsin L inhibitor. Z-Phe-Tyr(tBu)-diazomethylketone mediates reovirus disassembly. Z-Phe-Tyr(tBu)-diazomethylketone decreases viral detection[1][2].
Web ID
– HY-138208
Shipping
– Room temperature
Molecular Formula
– C31H34N4O5
References
– [1]Ebert DH, et al. Cathepsin L and cathepsin B mediate reovirus disassembly in murine fibroblast cells. J Biol Chem. 2002 Jul 5;277(27):24609-17.|[2]Perez-Bermejo JA, et al. SARS-CoV-2 infection of human iPSC-derived cardiac cells reflects cytopathic features in hearts of patients with COVID-19. Sci Transl Med. 2021 Apr 21;13(590):eabf7872.
CAS Number
– 114014-15-2
Molecular Weight
– 542.63
SMILES
– O=C(N[C@H](C(C=[N+]=[N-])=O)CC(C=C1)=CC=C1OC(C)(C)C)[C@@H](NC(OCC2=CC=CC=C2)=O)CC3=CC=CC=C3
Clinical Information
– No Development Reported
Research Area
– Infection
Solubility
– 10 mM in DMSO
Target
– Cathepsin;SARS-CoV
Isoform
– Cathepsin L
Pathway
– Anti-infection;Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
