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(Z)-Lafutidine
SKU
HY-121406-Get quote
Category Reference compound
Tags GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling, Histamine Receptor, Inflammation/Immunology
Products Details
Product Description
– (Z)-Lafutidine ((Z)-FRG-8813) is a potent histamine H2 receptor antagonist. (Z)-Lafutidine shows anti-secretory and gastroprotective activities[1].
Web ID
– HY-121406
Shipping
– Room temperature
Applications
– COVID-19-immunoregulation
Molecular Formula
– C22H29N3O4S
References
– [1]Hirakawa N, et al. A novel histamine 2(H2) receptor antagonist with gastroprotective activity. II. Synthesis and pharmacological evaluation of 2-furfuryl-thio and 2-furfurylsulfinyl acetamide derivatives with heteroaromatic rings. Chem Pharm Bull (Tokyo). 1998;46(4):616-622.
CAS Number
– 206449-93-6
Molecular Weight
– 431.55
SMILES
– O=C(NC/C=CCOC1=NC=CC(CN2CCCCC2)=C1)CS(CC3=CC=CO3)=O
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Histamine Receptor
Isoform
– H2 Receptor
Pathway
– GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling
Product type
– Reference compound
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