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YTP-17
$1,580
Only 1000 item(s) left in stock.
Products Details
Product Description
– YTP-17 is an orally active YAP-TEAD protein-protein interaction inhibitor with an IC50 of 4 nM. YTP-17 shows anti-tumor efficacy[1].
Web ID
– HY-150256
Storage Temperature
– 4°C (Powder, protect from light, stored under nitrogen)
Shipping
– Room Temperature
Molecular Formula
– C26H25ClF2N2O4
References
– [1]Holger Sellner, et al. Optimization of a Class of Dihydrobenzofurane Analogs toward Orally Efficacious YAP-TEAD Protein-Protein Interaction Inhibitors. ChemMedChem. 2023 Jun 1;18(11):e202300051.
Molecular Weight
– 502.94
Compound Purity
– 99.47
SMILES
– FC1=CC2=C([C@@]([C@@]3=C(C=CC(OCCO)=C3F)C(NC)=O)=C1Cl)C[C@](C4=CC=CC=C4)(CNC)O2
Clinical Information
– No Development Reported
Research Area
– Cancer
Solubility
– DMSO : ≥ 100 mg/mL
Target
– YAP
Pathway
– Stem Cell/Wnt
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.