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Products Details
Product Description
– YQA14 is a high affinity dopamine D3 receptor antagonist. YQA14 is anti-opioid addiction agent. YQA14 inhibits Morphine/Cocaine-induced conditioned place preference (CPP) in animals[1][2].
Web ID
– HY-116181
Shipping
– Room temperature
Molecular Formula
– C23H27ClN4O3
References
– [1]Hu R, et al. The dopamine D3 receptor antagonist YQA14 that inhibits the expression and drug-primed reactivation of morphine-induced conditioned place preference in rats. Eur J Pharmacol. 2013 Oct 24:S0014-2999(13)00782-6.|[2]Song R, et al. Dopamine D(3) receptor deletion or blockade attenuates cocaine-induced conditioned place preference in mice. Neuropharmacology. 2013 Sep;72:82-7.
CAS Number
– 1221408-42-9
Molecular Weight
– 442.94
SMILES
– O=C(NCCCCN1CCN(CC1)C2=CC(Cl)=CC=C2C)C3=CC=C4OC(NC4=C3)=O
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– Dopamine Receptor
Pathway
– GPCR/G Protein;Neuronal Signaling
Product type
– Reference compound
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