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Yonkenafil (hydrochloride)
$130 – $2,850
Products Details
Product Description
– Yonkenafil (Tunodafil) hydrochloride, a novel phosphodiesterase 5 (PDE5) inhibitor, is effective in reducing cerebral infarction, neurological deficits, edema, and neuronal damage in the infarcted area. Yonkenafil (Tunodafil) hydrochloride may improve cognitive function by modulating neurogenesis and has a potential therapeutic effect on Alzheimer’s disease[1].
Web ID
– HY-125095
Storage Temperature
– 4°C (Powder, sealed storage, away from moisture and light)
Shipping
– Room Temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C24H34ClN5O4S
References
– [1]Xuemei Chen, et al. Yonkenafil: a novel phosphodiesterase type 5 inhibitor induces neuronal network potentiation by a cGMP-dependent Nogo-R axis in acute experimental stroke. Exp Neurol. 2014 Nov;261:267-77.Â
CAS Number
– 804519-64-0
Molecular Weight
– 524.08
Compound Purity
– 99.43
SMILES
– O=C1C2=C(N=C(N1)C3=CC(S(=O)(N4CCN(CC4)CC)=O)=CC=C3OCC)N(C=C2C)CCC.[H]Cl
Clinical Information
– Phase 1
Research Area
– Neurological Disease; Cardiovascular Disease
Solubility
– DMSO : 100 mg/mL (ultrasonic)
Target
– Phosphodiesterase (PDE)
Isoform
– PDE5
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
