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YM976
$55 – $88
Products Details
Product Description
– YM976 is a phosphodiesterase 4 (PDE4) inhibitor with an IC50 of 2.2 nM. YM976 shows the dissociation of anti-inflammatory activities from emetic effects and inhibits the antigen-induced airway responses[1].
Web ID
– HY-108617
Storage Temperature
– -20°C (Powder, sealed storage, away from moisture)
Shipping
– Blue Ice
Applications
– COVID-19-immunoregulation
Molecular Formula
– C17H16ClN3O
References
– [1]Hiroshi Moriuchi, et al. Relaxant effect of YM976, a novel phosphodiesterase 4 inhibitor, on bovine tracheal smooth muscle. Eur J Pharmacol. 2003 May 30;470(1-2):57-64.
CAS Number
– 191219-80-4
Molecular Weight
– 313.78
Compound Purity
– 99.0
SMILES
– O=C1N(CC)C2=NC(CC)=CC=C2C(C3=CC=CC(Cl)=C3)=N1
Clinical Information
– No Development Reported
Research Area
– Inflammation/Immunology
Solubility
– 10 mM in DMSO
Target
– Phosphodiesterase (PDE)
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
