Download Files:
Products Details
Product Description
– YM90K is a potent and selective AMPA receptor antagonist with a Ki of 84 nM. YM90K is less potent in inhibiting kainate (Ki of 2.2 μM) and NMDA (Ki of 37 μM) receptors. YM90K has neuroprotective actions[1].
Web ID
– HY-15071
Shipping
– Room temperature
Applications
– Neuroscience-Neurodegeneration
Molecular Formula
– C11H8ClN5O4
References
– [1]M Shimizu-Sasamata, et al. YM90K: pharmacological characterization as a selective and potent alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate/kainate receptor antagonist. J Pharmacol Exp Ther. 1996 Jan;276(1):84-92.
CAS Number
– 154164-30-4
Molecular Weight
– 309.67
SMILES
– O=C1NC2=C(C=C(N3C=CN=C3)C([N+]([O-])=O)=C2)NC1=O.[H]Cl
Clinical Information
– No Development Reported
Research Area
– Neurological Disease
Solubility
– 10 mM in DMSO
Target
– iGluR
Isoform
– AMPA Receptor
Pathway
– Membrane Transporter/Ion Channel;Neuronal Signaling
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
