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YM511
$160 – $1,250
Products Details
Product Description
– YM511 is a highly specific non-steroidal aromatase inhibitor. YM511 inhibits aromatase activities in microsomes from rat ovary and human placenta competitively (IC50s of 0.4 and 0.12 nM, respectively). YM511 slightly inhibits production of other steroid hormones. YM511 has the potential for suppressing estrogen-dependent action research without affecting serum levels of other steroid hormones[1].
Web ID
– HY-105184
Storage Temperature
– 4°C (Powder, protect from light)
Shipping
– Room Temperature
Applications
– Metabolism-protein/nucleotide metabolism
Molecular Formula
– C16H12BrN5
References
– [1]M Kudoh, et al. The potent and selective inhibition of estrogen production by non-steroidal aromatase inhibitor, YM511. J Steroid Biochem Mol Biol. 1995 Sep;54(5-6):265-71.
CAS Number
– 148869-05-0
Molecular Weight
– 354.20
Compound Purity
– 99.73
SMILES
– BrC(C=C1)=CC=C1CN(N2C=NN=C2)C3=CC=C(C#N)C=C3
Clinical Information
– No Development Reported
Research Area
– Endocrinology
Solubility
– DMSO : 250 mg/mL (ultrasonic)
Target
– Cytochrome P450
Isoform
– CYP19
Pathway
– Metabolic Enzyme/Protease
Product type
– Reference compound
Disclaimer: All products are for Research use only unless clearly stated otherwise on the product datasheet. Datasheets provided on the website are drafts for reference purpose only and you are requested to always refer to the hard copy included in the kit for your experimentation. Agdia Products are available for delivery only in Canada.
